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National Research Council (US) Committee on Recognition and Alleviation of Pain in Laboratory Animals. Recognition and Alleviation of Pain in Laboratory Animals. Washington (DC): National Academies Press (US); 2009.

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Recognition and Alleviation of Pain in Laboratory Animals.

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In preparation for this report, the committee invited experts to present their perspectives on the concepts of nociception, pain, consciousness, and awareness. The committee thanks:

Colin Allen, Indiana University

A. Vania Apkarian, Northwestern University

David Borsook, McLean Hospital

This report was reviewed in draft form by individuals chosen for their diverse perspectives and technical expertise, in accordance with procedures approved by the Report Review Committee of the National Research Council (NRC). The purpose of this independent review is to provide candid and critical comments that will assist the committee in making its published report as sound as possible and to ensure that the report meets institutional standards for objectivity, evidence, and responsiveness to the study charge. The review comments and draft manuscript remain confidential to protect the integrity of the deliberation process. The committee thanks the following individuals for their review of this report:

K. S. Anand, University of Arkansas for Medical Sciences

George J. DeMarco, Pfizer, Inc.

Ronald Dubner, University of Maryland

Sherril Green, Stanford School of Medicine

C. Terrance Hawk, GlaxoSmithKline Pharmaceuticals R&D

B. Duncan X. Lascelles, North Carolina State College of Veterinary Medicine

Jerald Silverman, University of Massachusetts Medical School

William S. Stokes, National Institute of Environmental and Health Sciences

Daniel M. Weary, University of British Columbia, Canada

Tony L. Yaksh, University of California—San Diego

Although the reviewers listed above provided many constructive comments and suggestions, they were not asked to endorse the report’s conclusions or recommendations, nor did they see the final draft of the report before its release. The review of this report was overseen by Hilton J. Klein, Taconic, and Harley W. Moon, Iowa State University (emeritus). Appointed by the NRC, they were responsible for making certain that an independent examination of this report was carried out in accordance with institutional procedures and that all review comments were carefully considered. Responsibility for the final content of this report rests entirely with the authoring committee and the institution.

This report is the product of committee members who gave generously of their time and effort. The committee rapidly developed into a collegial, hard-working group, freely shared ideas, debated contentious issues enthusiastically, and strived to make this report both useful and informative to readers. We grew in the process and learned from each other. I deeply appreciate the members’ contributions and insistence on applying an evidence-based approach to the content and recommendations in the report. Their efforts would not have been successful without the invaluable help of ILAR staff and committee consultants, particularly Lida Anestidou and Heidi Shafford, respectively, who each deserve our sincere thanks. I am deeply appreciative of the opportunity to have been a part of this effort and anticipate that the report will meet its principal objectives.

Gerald F. Gebhart, Chair

Committee on Recognition and Alleviation of Pain in Laboratory Animals

Copyright © 2009, National Academy of Sciences.
Bookshelf ID: NBK32649
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