Evidence table 23

Description of RCTs addressing the impact of CHI applications on intermediate outcomes in mental health

Author, yearConsumer under studyCHI Application typeLocationYear data collected/ duration of interventionInclusion criteriaExclusion criteriaControlInterventionJadad score
Christensen, 20041Individual interested in their own health careInteractive consumer websiteNSNS≥18 yr, Internet access, 22 or higher on the Kessler psychological distress scale>52 yr, receiving clinical care from either a psychologist or psychiatristControlMood GYM, Blue Pages 2
Neil, 20092Depressed/Anxious youthInteractive consumer websiteSchool – classroom / community2006–07Adolescents 13 – 17 yrs completing the YouthMood projectNSUse of website (open access) in communityUse of website (open access) in classroom
Proudfoot, 20043Individual interested in their own health careComputerized cognitive behavioral therapyClinician officeNS18–75 yr, Depression, Anxiety and depression, Anxiety, Not currently receiving any form of psychological treatment or counseling, Score of 4 or more on the 12 item general health questionnaire, 12 or more on the computer version of the Clinical Interview Schedule-RevisedActive suicidal ideas, Diagnosis of psychosis or organic mental disorder, alcohol and/or drug dependence, Medication for anxiety and/or depression continuously for 6 months or more immediately prior to entry, Unable to attend 8 sessions at the surgery, Unable to read or write EnglishTreatment as usualComputerized therapy 3
Warmerdam,20084Depressed / AnxiousInteractive Consumer websiteHome / res08-09/06 – 01-02/07>18 yrs, Score of >=16 on CES-D, knew Dutch, internet and email accessCES-D scores greater than 32Wait-listed controlsInteractive computer tool based on Cog. Beh. Theory and Prob. Sol. Theory
Schneider, 20055Individual interested in their own health careWeb based tailored self help informationHome/ residence, Remote location: preferred site of patientNSFulfill ICD-10 criteria for agoraphobia with/without panic disorder, social phobia or specific phobia, 4≥ for global phobia, Main goal negotiated and set with clinician, phobia for more than one year, Men: alcohol <21 units/week, Women: alcohol <14 units/week, No reading disorder hindering net useCurrent psychotic illness, suicide plans, no severe depression, disabling cardiac or respiratory disease, On benzodiazepine or diazepam equivalent dose of >5 mg/day, began or changed dose or type of antidepressant within the last 4 weeks, Substance abuse, Failed past exposure therapy of >4 sessionsManaging Anxiety application,
Fear Fighter application
Chiauzzi, 20086Interactive consumer website,University2005≥18 and ≤24 yr, college students, scoring above 14 on theA control website (CW)MyStudentBody–Stress website,
No treatment control (NTX)
Hasson, 20057Individual interested in their own health carePersonal monitoring deviceNSNSEmployment at a company insured by Alecta (occupational pension plan company)those who quit employment prior to completion of study, “communication related problem”Access to web-based toolWeb-based tool with control group components plus self-help with stress management exercises and chat 2
Stress Management
Zetterqvist, 20038For stress management for gen populationInteractive consumer webHome / res04/2000 – 06-07/2000No specified inclusion or exclusion criteria unless the participant expressed a condition that would prevent him / her from completing the studyControlInteractive self help stress management program

NS = not specified, Yr = year

Reference List


Christensen H, Griffiths KM, Jorm AF. Delivering interventions for depression by using the internet: randomised controlled trial. BMJ 2004; 328(7434):265.


Neil AL, Batterham P, Christensen H, Bennett K, Griffiths KM. Predictors of adherence by adolescents to a cognitive behavior therapy website in school and community-based settings. J Med Internet Res 2009; 11(1):e6.


Proudfoot J, Ryden C, Everitt B et al. Clinical efficacy of computerised cognitive-behavioural therapy for anxiety and depression in primary care: randomised controlled trial. Br J Psychiatry 2004; 185:46–54.


Warmerdam L, van Straten A, Twisk J, Riper H, Cuijpers P. Internet-based treatment for adults with depressive symptoms: randomized controlled trial. J Med Internet Res 2008; 10(4):e44.


Schneider AJ, Mataix-Cols D, Marks IM, Bachofen M. Internet-guided self-help with or without exposure therapy for phobic and panic disorders. Psychother Psychosom 2005; 74(3):154–64.


Chiauzzi E, Brevard J, Thurn C, Decembrele S, Lord S. MyStudentBody-Stress: an online stress management intervention for college students. J Health Commun 2008; 13(6):555–72.


Hasson D, Anderberg UM, Theorell T, Arnetz BB. Psychophysiological effects of a web-based stress management system: a prospective, randomized controlled intervention study of IT and media workers. BMC Public Health 2005; 5:78.


Zetterqvist K, Maanmies J, Str+¦m L, Andersson G. Randomized controlled trial of internet-based stress management. 2003; 32(3):151–60.

From: Appendix G

Cover of Impact of Consumer Health Informatics Applications
Impact of Consumer Health Informatics Applications.
Evidence Reports/Technology Assessments, No. 188.
Gibbons MC, Wilson RF, Samal L, et al.

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