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Nussey S, Whitehead S. Endocrinology: An Integrated Approach. Oxford: BIOS Scientific Publishers; 2001.

Cover of Endocrinology

Endocrinology: An Integrated Approach.

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Box 6.30The major steroidogenic pathway in the human testis

Image ch6fb30.jpg

Testosterone and smaller amounts of androstenedione not only enter the circulation but diffuse into the seminiferous tubules where they may bind directly to androgen receptors or first be converted to dihydrotestosterone. Small amounts of estradiol are also formed in both cell types, perferentially in the Sertoli cells prepubertally and in the Leydig cells postpubertally.

+, conversions stimulated by 17β-hydroxysteroid dehydrogenase; *, conversions stimulated by aromatase.

From: Chapter 6, The gonad

Copyright © 2001, BIOS Scientific Publishers Limited.

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