Figure 19. Evidence for light adaptation in ipRGCs.

Figure 19

Evidence for light adaptation in ipRGCs. (a) Current-clamp recording from an ipRGC with test pulses flashed on top of a background light. The cell decreases its sensitivity to the background light over time and is able to generate a larger response to the test pulse towards the end of the recording compared to the response to the same test pulse right after onset of the background light. (b) Summary data for current clamp recordings from five ipRGCs. (c) Voltage-clamp recording using same conditions as (a) showing similar adaptation to the background light. (d) Summary data for voltage-clamp recordings from five ipRGCs. Adapted from Wong KY, Dunn FA, et al. (2005). "Photoreceptor adaptation in intrinsically photosensitive retinal ganglion cells." Neuron. 48(6): 1001-10.

From: Melanopsin Ganglion Cells: A Bit of Fly in the Mammalian Eye

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Webvision: The Organization of the Retina and Visual System [Internet].
Kolb H, Fernandez E, Nelson R, editors.
Salt Lake City (UT): University of Utah Health Sciences Center; 1995-.

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