Figure 18-16. Kinetochore microtubules.

Figure 18-16Kinetochore microtubules

(A) A fluorescence micrograph of a metaphase chromosome stained with a DNA-binding fluorescent dye and with human autoantibodies that react with specific kinetochore proteins. The two kinetochores, one associated with each chromatid, are stained red. (B) A drawing of a metaphase chromosome showing its two sister chromatids attached to kinetochore microtubules, which bind by their plus ends. Each kinetochore forms a plaque on the surface of the centromere. The number of microtubules bound to a metaphase kinetochore varies from 1 in budding yeast to over 40 in some mammalian cells. (A, courtesy of B.R. Brinkley.)

From: Mitosis

Cover of Molecular Biology of the Cell
Molecular Biology of the Cell. 4th edition.
Alberts B, Johnson A, Lewis J, et al.
New York: Garland Science; 2002.
Copyright © 2002, Bruce Alberts, Alexander Johnson, Julian Lewis, Martin Raff, Keith Roberts, and Peter Walter; Copyright © 1983, 1989, 1994, Bruce Alberts, Dennis Bray, Julian Lewis, Martin Raff, Keith Roberts, and James D. Watson .

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