Figure 1. Comparison of the chromosomal organization of the two sequenced H.

Figure 1

Comparison of the chromosomal organization of the two sequenced H. pylori genomes. The continuous outer circle represents the H. pylori 26695 genome whereas the inner circle represents the organization of the H. pylori J99 genome relative to that of strain 26695, incorporating artificial breaks to facilitate the alignment as described in the text and elsewhere (8). The artificial breaks are represented by encircled numbers and represent inversions and/or translocations. The locations of complete (circle) or partial (half-circle) IS605 (filled) and IS606 (open) insertion elements in both chromosomes are indicated, and the five cases of coincident location are indicated by an asterisk (*) between the circles. The location and number of strain-specific genes (found in one strain but not the other) are indicated by vertical marks crossing the respective chromosome. At loci where both genomes possess strain-specific genes at the same position, the vertical mark crosses both genomic circles. The strain-specific genes boxed represent HP1383 and HP1404, which are found at either endpoint of genomic rearrangement 8. In this figure, the mpA and mpB genes of the IS605 and IS606 elements (a total of 2 in J99 and 14 in 26695) are included with the strain-specific genes. The location of the one and two plasticity zone(s) in J99 and 26695, respectively, are represented by stars (★).

From: Chapter 27, The Genome

Cover of Helicobacter pylori
Helicobacter pylori: Physiology and Genetics.
Mobley HLT, Mendz GL, Hazell SL, editors.
Washington (DC): ASM Press; 2001.
Copyright © 2001, ASM Press.

NCBI Bookshelf. A service of the National Library of Medicine, National Institutes of Health.