Box 5.6Vitamin D synthesis

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Vitamin D3 synthesis in the skin is stimulated by sunlight and subsequent hydroxylations in the liver (at C-25) and kidney (at C-1) produce the active form of the hormones. In the circulation vitamin D3 is bound to transcalciferin with only a small fraction in free form. Approximate half-lives (t1/2) of the active and inactive metabolites are also shown.

From: Chapter 5, The parathyroid glands and vitamin D

Cover of Endocrinology
Endocrinology: An Integrated Approach.
Nussey S, Whitehead S.
Copyright © 2001, BIOS Scientific Publishers Limited.

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