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National Research Council (US) Committee on How Toxicogenomics Could Inform Critical Issues in Carcinogenic Risk Assessment of Environmental Chemicals. Toxicogenomic Technologies and Risk Assessment of Environmental Carcinogens: A Workshop Summary. Washington (DC): National Academies Press (US); 2005.

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Toxicogenomic Technologies and Risk Assessment of Environmental Carcinogens: A Workshop Summary.

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Appendix CAbbreviations

Ahr

aryl hydrocarbon receptor

ADH

alcohol dehydrogenase

cDNA

complementary deoxyribonucleic acid

CYP1B1

cytochrome P450, isozyme 1B1

CYP2A6

cytochrome P450, isozyme 2A6

CYP2E1

cytochrome P450, isozyme 2E1

CYP3A4

cytochrome P450, isozyme 3A4

DNA

deoxyribonucleic acid

EH

epoxide hydrolase

EPA

U.S. Environmental Protection Agency

E2

Estrogen

FDA

U.S. Food and Drug Administration

GAO

U.S. Government Accountability Office

GST

glutathione S-transferase

IARC

International Agency for Research on Cancer

IGFbp5

insulin-like growth factor-binding protein-5

LOX

lysyl oxidase

MOA

mode-of-action

mRNA

messenger ribonucleic acid

MTD

maximal tolerated dose

NIEHS

National Institute of Environmental Health Sciences

NIH

National Institutes of Health

NOAEL

no-observed-adverse-effects level

OHT

4-hydroxytamoxifen

OPN

osteopontin

PCR

polymerase chain reaction

PGME

propylene glycol monomethyl ether

RNA

ribonucleic acid

SAR

structure-activity relationship

SNP

single-nucleotide polymorphisms

Copyright © 2005, National Academy of Sciences.
Bookshelf ID: NBK23735

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