Figure 31.31. Cyclic AMP-Response Element Binding Protein (CREB).

Figure 31.31Cyclic AMP-Response Element Binding Protein (CREB)

Figure 31.31. Cyclic AMP-Response Element Binding Protein (CREB). Each of two CREB subunits contributes a long α helix. The two helices coil around each other to form a dimeric DNA-binding unit. CREB is phosphorylated on a specific serine residue by protein kinase A.

From: Section 31.3, Transcriptional Activation and Repression Are Mediated by Protein-Protein Interactions

Cover of Biochemistry
Biochemistry. 5th edition.
Berg JM, Tymoczko JL, Stryer L.
New York: W H Freeman; 2002.
Copyright © 2002, W. H. Freeman and Company.

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