Figure 21.22. Glucose Regulation of Liver Glycogen Metabolism.

Figure 21.22Glucose Regulation of Liver Glycogen Metabolism

Glucose binds to and inhibits glycogen phosphorylase a in the liver, leading to the dissociation and activation of protein phosphatase 1 (PP1) from glycogen phosphorylase a. The free PP1 dephosphorylates glycogen phosphorylase a and glycogen synthase b, leading to the inactivation of glycogen breakdown and the activation of glycogen synthesis.

Cover of Biochemistry
Biochemistry. 5th edition.
Berg JM, Tymoczko JL, Stryer L.
New York: W H Freeman; 2002.

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