Figure 33.24. Class I MHC Peptide-Binding Site.

Figure 33.24Class I MHC Peptide-Binding Site

Figure 33.24. Class I MHC Peptide-Binding Site. The α1and α2domains come together to form a groove in which peptides are displayed. The two views shown reveal that the peptide is surrounded on three sides by a β sheet and two α helices, but it is accessible from the top of the structure.

From: Section 33.5, Major-Histocompatibility-Complex Proteins Present Peptide Antigens on Cell Surfaces for Recognition by T-Cell Receptors

Cover of Biochemistry
Biochemistry. 5th edition.
Berg JM, Tymoczko JL, Stryer L.
New York: W H Freeman; 2002.
Copyright © 2002, W. H. Freeman and Company.

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