Figure 33.23. Class I MHC Protein.

Figure 33.23Class I MHC Protein

Figure 33.23. Class I MHC Protein. A protein of this class consists of two chains. The α chain begins with two domains that include α helices (α1, α2), an immunoglobulin domain (α3), a transmembrane domain, and a cytoplasmic tail. The second chain, β2-microglobulin, adopts an immunoglobulin fold.

From: Section 33.5, Major-Histocompatibility-Complex Proteins Present Peptide Antigens on Cell Surfaces for Recognition by T-Cell Receptors

Cover of Biochemistry
Biochemistry. 5th edition.
Berg JM, Tymoczko JL, Stryer L.
New York: W H Freeman; 2002.
Copyright © 2002, W. H. Freeman and Company.

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