Figure 8.6. Insulators maintain the independence of a functional domain.

Figure 8.6Insulators maintain the independence of a functional domain

(A) When placed between a gene and its upstream regulatory modules, an insulator sequence prevents the regulatory signals from reaching the gene. (B) In their normal positions, insulators prevent cross-talk between functional domains, so the regulatory modules of one gene do not influence expression of a gene in a different domain. For more details about regulatory modules, see Box 9.6.

From: Chapter 8, Accessing the Genome

Cover of Genomes
Genomes. 2nd edition.
Brown TA.
Oxford: Wiley-Liss; 2002.
Copyright © 2002, Garland Science.

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