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Brown TA. Genomes. 2nd edition. Oxford: Wiley-Liss; 2002.

Cover of Genomes

Genomes. 2nd edition.

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Part 1Genomes, Transcriptomes and Proteomes

Part 1 of Genomes introduces the central concepts of modern molecular biology. In these three chapters you will become familiar with the genomes of the different types of organism that live on planet Earth and you will begin to understand the link between the genome, transcriptome and proteome.

Chapter 1 explains how the structure of DNA enables this molecule to perform its role as a store of biological information, and also describes the construction of the human genome, as revealed by the draft DNA sequence that was completed in 2001.

In Chapter 2 we broaden our focus by surveying the genomes of other organisms, including plants, insects, yeast, bacteria and archaea. As you read this chapter, you will realize that our perception of the basic principle of life – how an organism’s biological information is stored in its genome – is undergoing rapid change as more and more genome sequences are being completed.

Chapter 3 explains that these conceptual changes encompass not only the genome itself but also the processes by which the information contained in the genome is utilized by the cell. You will learn how the old-fashioned notions of gene expression are now being redefined as genome expression, and you will discover how the flow of biological information from genome to cell involves synthesis and maintenance of the transcriptome and the proteome.

Chapter 1. The Human Genome

Chapter 2. Genome Anatomies

Chapter 3. Transcriptomes and Proteomes

Copyright © 2002, Garland Science.
Bookshelf ID: NBK21125


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