Figure 9.22. Primary and secondary levels of gene regulation.

Figure 9.22Primary and secondary levels of gene regulation

According to this scheme, ‘primary’ regulation of genome expression occurs at the level of transcription initiation, this step determining which genes are expressed in a particular cell at a particular time and setting the relative rates of expression of those genes that are switched on. ‘Secondary’ regulation involves all steps in the gene expression pathway after transcription initiation, and serves to modulate the amount of protein that is synthesized or to change the nature of the protein in some way, for example by chemical modification.

From: Chapter 9, Assembly of the Transcription Initiation Complex

Cover of Genomes
Genomes. 2nd edition.
Brown TA.
Oxford: Wiley-Liss; 2002.
Copyright © 2002, Garland Science.

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