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Figure 14.5. Replication slippage.

Figure 14.5Replication slippage

The diagram shows replication of a five-unit CA repeat microsatellite. Slippage has occurred during replication of the parent molecule, inserting an additional repeat unit into the newly synthesized polynucleotide of one of the daughter molecules. When this daughter molecule replicates it gives a granddaughter molecule whose microsatellite array is one unit longer than that of the original parent.

From: Chapter 14, Mutation, Repair and Recombination

Cover of Genomes
Genomes. 2nd edition.
Brown TA.
Oxford: Wiley-Liss; 2002.
Copyright © 2002, Garland Science.

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