Table 111.2Classification and Staging of Vulvar Carcinoma

TNM Classification
TPrimary tumor
TisPreinvasive carcinoma (carcinoma in situ)
T1Tumor confined to the vulva and /or perineum; 2 cm or less in diameter
T2Tumor confined to the vulva and/or perineum; more than 2 cm in diameter
T3Tumor of any size with adjacent spread to the urethra, vagina, or anus
T4Tumor of any size infiltrating the bladder mucosa or the rectal mucosa or both, including the upper part of the urethral mucosa, or fixed to the anus
NRegional lymph nodes
N0No nodes palpable
N1Unilateral regional lymph node metastases
N2Bilateral regional lymph node metastases
MDistant metastases
M0No clinical metastases
M1Distant metastases (including pelvic lymph node metastases)
FIGO Staging (1988)
Stage 0TisCarcinoma in situ
Intraepithelial carcinoma
Stage IT1 N0 M0Tumor confined to the vulva and/or perineum; 2 cm or less in greatest dimension. No nodal metastasis
Stage IIT2 N0Tumor confined to the vulva and/or perineum; more than 2 cm in greatest dimension. No nodal metastasis
Stage IIIT3 N0 M0Tumor of any size with (1) Adjacent spread and/or the anus and/or (2) unilateral regional lymph node metastasis
T1 N1 M0
T2 N1 M0
T3 N1 M0
Stage IVAT1 N2 M0Tumor invades any of the following: upper urethra, bladder mucosa, rectal mucosa, pelvic bone, and/or bilateral regional node metastasis
T2 N2 M0
T3 N2 M0
T4, any N, M0
Stage IVBAny T, any N, M1Any distant metastasis including pelvic lymph nodes

TNM = tumors, nodes, metastases; FIGO = International Federation of Gynecology and Obstetrics. Source: Creasman WT. New gynecologic cancer staging. Obstet Gynecol 1990;75:287.

From: Chapter 111, Neoplasms of the Vulva and Vagina

Cover of Holland-Frei Cancer Medicine
Holland-Frei Cancer Medicine. 5th edition.
Bast RC Jr, Kufe DW, Pollock RE, et al., editors.
Hamilton (ON): BC Decker; 2000.
© 2000, BC Decker Inc.

NCBI Bookshelf. A service of the National Library of Medicine, National Institutes of Health.