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Table 53.3Structures of Bombesin, Gastrin Releasing Peptide and Neuromedin B

Bombesin
pGlu-Gln-Arg-Leu-Gly-Asn-Gln-Trp-Ala-Val-Gly-His-Leu-Met-NH2
1234567891011121314
Gastrin-releasing peptide (human)
Val-Pro-Leu-Pro-Ala-Gly-Gly-Gly-Thr-Val-Leu-Thr-Lys-
Met-Tyr-Pro-Arg-Gly-Asn-His-Trp-Ala-Val-Gly-His-Leu-Met-NH2
1415161718192021222324252627
Neuromedin B
Gly-Asn-Leu-Trp-Ala-Thr-Gly-His-Phe-Met-NH2
12345678910

Sequence homologies relative to bombesin are underlined.

In analogues, ψ(psi) indicates a reduced (pseudo) peptide bond (-CH2-NH-).

From: Chapter 53, Hypothalamic and Other Peptide Hormones

Cover of Holland-Frei Cancer Medicine
Holland-Frei Cancer Medicine. 5th edition.
Bast RC Jr, Kufe DW, Pollock RE, et al., editors.
Hamilton (ON): BC Decker; 2000.
© 2000, BC Decker Inc.

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