TABLE E.1 Pharyngeal Cancer and Exposure to Asbestos—Case-Control Studies

Reference*Study Population Exposed Cases Estimated RR (95% CI)
Berrino et al. 2003100 male cases of hypopharyngeal cancer from six centers in Southern Europe, < 55 years old (adjusted for smoking and alcohol consumption)
      Possible na 1.8 (0.9-3.9)
      Probable na1.8 (0.6-5.0)
      (More detailed findings from combined analysis with 215 cases of laryngeal cancer on Table E.2)
Luce et al. 20005 hypopharyngeal cancer cases among residents of New Caledonia
      Whitewash from tremolite asbestos 10.64 (0.01-6.68)
Marchand et al. 2000206 hypopharyngeal cancer cases among male residents of six cities in France (adjusted for smoking and alcohol consumption)
      Any exposure 1611.80 (1.08-2.99)
      Low cumulative exposure 52 1.92 (1.03-3.57)
      Intermediate 52 1.40 (0.74-2.63)
      High 57 2.14 (1.14-4.01)
Gustavsson et al. 1998138 pharyngeal cancer cases among male residents of two regions in Sweden (adjusted for smoking and alcohol consumption)
      Asbestos (low) 24 1.01 (0.57-1.80)
      Asbestos (high) 22 1.08 (0.62-1.91)
Zheng et al. 1992b115 male oral or pharyngeal cancer cases among residents of Shanghai, China Asbestos, occupational exposure 161.81 (0.91-3.60)a
Merletti et al. 199186 oral cavity or oropharynx (n = 12) cancer cases among male residents of Turin, Italy (adjusted for smoking and alcohol consumption)
      Any exposure 451.1 (na)
      Probable or definite 30.4 (na)

NOTES: CI = Confidence interval; na = not available; RR = relative risk. Data points included in meta-analyses are bolded.

*

Full citations can be found in the reference list for Chapter 6.

a

OR and 95% CI calculated with standard methods from observed numbers of exposed cases and controls in original paper.

From: E, Case-Control Results Tables

Cover of Asbestos
Asbestos: Selected Cancers.
Institute of Medicine (US) Committee on Asbestos: Selected Health Effects.
Washington (DC): National Academies Press (US); 2006.
Copyright © 2006, National Academy of Sciences.

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