Figure 5. Role of HOM-C genes in patterning the P cells (ventral ectoderm) in the male nematode.

Figure 5

Role of HOM-C genes in patterning the P cells (ventral ectoderm) in the male nematode. (A,B) Location and division pattern of P cells; (C) overall domains of HOM-C gene activity. Distribution of Mab-5 protein and staining for lin-39 -lacZ expression coincide with the indicated (filled) domains. (D) Fates of the individual descendants of each P cell. (A,B,S,D) Motor neuron types called VA, VB, AS, and DD, respectively. (E) Division to produce one cell death and one rectal epithelial cell; (F) fusion; (U) lack of fusion with the epidermal syncytium; (M) division to produce a pair of motor neurons (one serotonergic); (I) division to produce one interneuron and one neuron-like cell; (X) programmed cell death; (N,P,V,Z) other types of neurons. Colors indicate the dependence of these fates on lin-39 (red), mab-5 (yellow), egl-5 (blue), or lin-39 plus mab-5 (orange). Yellow cross-hatching indicates variable mab-5 activity in promoting the I fate in a lin-39 () background. Red cross-hatching indicates lin-39 activity in promoting the N fate, which extends beyond the domain of other lin-39 activities and beyond detectable lin-39 -lacZ expression. (Reprinted, with permission, from Salser and Kenyon 1994.)

From: Section IV, Generation of Reiterated Neurons by Reiterated Cell Lineages

Cover of C. elegans II
C. elegans II. 2nd edition.
Riddle DL, Blumenthal T, Meyer BJ, et al., editors.
Cold Spring Harbor (NY): Cold Spring Harbor Laboratory Press; 1997.
Copyright © 1997, Cold Spring Harbor Laboratory Press.

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