Figure 3. Models for retroviral structure.

Figure 3

Models for retroviral structure. (Models courtesy of Lou Henderson.) (Top) The immature HIV-1 virion. The Gag and Gag-Pol proteins are shown with different colors to suggest the domains corresponding to the mature proteins formed from these precursors. The SU and TM components of Env are shown jutting out from the lipid membrane, as are HLA host proteins selectively incorporated into HIV particles. Cyclophilin also is a host protein specific for HIV-1 virions. See text for details. (Bottom) The mature HIV-1 virion. The major Gag and Pol proteins and the cone-shaped core characteristic of viruses of this genus are shown. Vpr is an HIV accessory protein. See text for details.

From: Models for Virion Structure

Cover of Retroviruses
Coffin JM, Hughes SH, Varmus HE, editors.
Cold Spring Harbor (NY): Cold Spring Harbor Laboratory Press; 1997.
Copyright © 1997, Cold Spring Harbor Laboratory Press.

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