FIGURE 46.4. Pleiotropic effects of mutations in UDP-Glc/UDP-GlcNAc-4-epimerase.

FIGURE 46.4

Pleiotropic effects of mutations in UDP-Glc/UDP-GlcNAc-4-epimerase. ldlD mutant CHO cells may be rescued by salvage reactions that generate the UDP-Gal and UDP-GalNAc necessary for the synthesis of many classes of glycans.

Symbol Key: FIGURE 46.4. Pleiotropic effects of mutations in UDP-Glc/UDP-GlcNAc-4-epimerase.

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From: Chapter 46, Glycosylation Mutants of Cultured Cells

Cover of Essentials of Glycobiology
Essentials of Glycobiology. 2nd edition.
Varki A, Cummings RD, Esko JD, et al., editors.
Cold Spring Harbor (NY): Cold Spring Harbor Laboratory Press; 2009.
Copyright © 2009, The Consortium of Glycobiology Editors, La Jolla, California.

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