Contents

• Foreword
  Jo McEntyre, Section Chief and David Lipman, Director.
• Foreword from First Edition
  Stuart Kornfeld.
• Preface
  Ajit Varki.
• Preface from First Edition
  Ajit Varki, for The Editors.
• Contributors
  • Executive Editor
  • Editors
  • Co-authors
• Acknowledgments
  • Consultants
  • Reviewers
• Books and Monograph Resources
• Abbreviations
• Part I. General Principles
  • 1. Historical Background and Overview
    Ajit Varki and Nathan Sharon.
  • 2. Structural Basis of Glycan Diversity
    Carolyn R Bertozzi and David Rabuka.
  • 3. Cellular Organization of Glycosylation
    Ajit Varki, Jeffrey D Esko, and Karen J Colley.
  • 4. Glycosylation Precursors
    Hudson H Freeze and Alan D Elbein.
  • 5. Glycosyltransferases and Glycan-processing Enzymes
    James Rini, Jeffrey Esko, and Ajit Varki.
  • 6. Biological Roles of Glycans
    Ajit Varki and John B Lowe.
  • 7. A Genomic View of Glycobiology
    Bernard Henrissat, Avadesha Surolia, and Pamela Stanley.
• Part II. Structure and Biosynthesis
  • 8. N-Glycans
    Pamela Stanley, Harry Schachter, and Naoyuki Taniguchi.
  • 9. O-GalNAc Glycans
    Inka Brockhausen, Harry Schachter, and Pamela Stanley.
  • 10. Glycosphingolipids
    Ronald L Schnaar, Akemi Suzuki, and Pamela Stanley.
  • 11. Glycosylphosphatidylinositol Anchors
    Michael AJ Ferguson, Taroh Kinoshita, and Gerald W Hart.
  • 12. Other Classes of ER/Golgi-derived Glycans
    Hudson H Freeze and Robert S Haltiwanger.
  • 13. Structures Common to Different Glycans
    Pamela Stanley and Richard D Cummings.
  • 14. Sialic Acids
    Ajit Varki and Roland Schauer.
  • 15. Hyaluronan
    Vince Hascall and Jeffrey D Esko.
  • 16. Proteoglycans and Sulfated Glycosaminoglycans
    Jeffrey D Esko, Koji Kimata, and Ulf Lindahl.
  • 17. Nucleocytoplasmic Glycosylation
    Gerald W Hart and Christopher M West.
  • 18. The O-GlcNAc Modification
    Gerald W Hart and Yoshihiro Akimoto.
• Part III. Organismal Diversity
  • 19. Evolution of Glycan Diversity
    Ajit Varki, Hudson H Freeze, and Pascal Gagneux.
  • 20. Eubacteria and Archaea
    Jeffrey D Esko, Tamara L Doering, and Christian RH Raetz.
  • 21. Fungi
    Richard D Cummings and Tamara L Doering.
  • 22. Viridiplantae
    Marilynn E Etzler and Debra Mohnen.
  • 23. Nematoda
    Richard D Cummings and Jeffrey D Esko.
  • 24. Arthropoda
    Michael Tiemeyer, Scott B Selleck, and Jeffrey D Esko.
  • 25. Deuterostomes
    Hudson H Freeze, Victor D Vacquier, and Jeffrey D Esko.
• Part IV. Glycan-binding Proteins
  • 26. Discovery and Classification of Glycan-Binding Proteins
    Ajit Varki, Marilynn E Etzler, Richard D Cummings, and Jeffrey D Esko.
  • 27. Principles of Glycan Recognition
    Richard D Cummings and Jeffrey D Esko.
  • 28. R-type Lectins
    Richard D Cummings and Marilynn E Etzler.
  • 29. L-type Lectins
    Marilynn E Etzler, Avadhesha Surolia, and Richard D Cummings.
  • 30. P-type Lectins
    Ajit Varki and Stuart Kornfeld.
  • 31. C-type Lectins
    Richard D Cummings and Rodger P McEver.
  • 32. I-type Lectins
    Ajit Varki and Paul R Crocker.
  • 33. Galectins
    Richard D Cummings and Fu-Tong Liu.
  • 34. Microbial Lectins: Hemagglutinins, Adhesins, and Toxins
    Jeffrey D Esko and Nathan Sharon.
  • 35. Proteins that Bind Sulfated Glycosaminoglycans
    Jeffrey D Esko and Robert J Linhardt.
• Part V. Glycans in Physiology and Disease
  • 36. Glycans in Glycoprotein Quality Control
    Hudson H Freeze, Jeffrey D Esko, and Armando J Parodi.
  • 37. Free Glycans as Signaling Molecules
    Marilynn E Etzler and Jeffrey D Esko.
  • 38. Glycans in Development and Systemic Physiology
    Ajit Varki, Hudson H Freeze, and Victor D Vacquier.
  • 39. Bacterial and Viral Infections
    Victor Nizet and Jeffrey D Esko.
  • 40. Parasitic Infections
    Richard Cummings and Salvatore Turco.
  • 41. Genetic Disorders of Glycan Degradation
    Hudson H Freeze.
  • 42. Genetic Disorders of Glycosylation
    Hudson H Freeze and Harry Schachter.
  • 43. Glycans in Acquired Human Diseases
    Ajit Varki and Hudson H Freeze.
  • 44. Glycosylation Changes in Cancer
    Ajit Varki, Reiji Kannagi, and Bryan P Toole.
• Part VI. Methods and Applications
  • 45. Antibodies and Lectins in Glycan Analysis
    Richard D Cummings and Marilynn E Etzler.
  • 46. Glycosylation Mutants of Cultured Cells
    Jeffrey D Esko and Pamela Stanley.
  • 47. Structural Analysis of Glycans
    Barbara Mulloy, Gerald W Hart, and Pamela Stanley.
  • 48. Glycomics
    Carolyn R Bertozzi and Ram Sasisekharan.
  • 49. Chemical and Enzymatic Synthesis of Glycans and Glycoconjugates
    Peter H Seeberger, Nathaniel Finney, David Rabuka, and Carolyn R Bertozzi.
  • 50. Chemical Tools for Inhibiting Glycosylation
    Jeffrey D Esko and Carolyn R Bertozzi.
  • 51. Glycans in Biotechnology and the Pharmaceutical Industry
    Carolyn R Bertozzi, Hudson H Freeze, Ajit Varki, and Jeffrey D Esko.
• Glossary
• Study Guide
  • Study Questions
• Errata
  • August 2011
  • January 2011
  • March 2010
  • December 2009
  • October 2009
  • August 2009
  • January 2009
  • December 2008