TABLE 9.2

Glycosyltransferases specific for mucin O-GalNAc glycans

EnzymeShort form
Polypeptide N-acetylgalactosaminyltransferaseppGalNAcT-1 to -24
Core 1 β1-3 galactosyltransferaseC1GalT-1 or T synthase
Core 2 β1-6 N-acetylglucosaminyltransferaseC2GnT-1, C2GnT-3
Core 3 β1-3 N-acetylglucosaminyltransferaseC3GnT-1
Core 2/4 β1-6 N-acetylglucosaminyltransferaseC2GnT-2
Elongation β1-3 N-acetylglucosaminyltransferaseelongation β3GnT-1 to -8
Core 1 α2-3 sialyltransferaseST3Gal I, ST3Gal IV
α2-6 sialyltransferaseST6GalNAc I, II, III or IV
Core 1 3-O-sulfotransferaseGal3ST4
Secretor gene α1-2 fucosyltransferaseFucT-I, FucT-II

From: Chapter 9, O-GalNAc Glycans

Cover of Essentials of Glycobiology
Essentials of Glycobiology. 2nd edition.
Varki A, Cummings RD, Esko JD, et al., editors.
Cold Spring Harbor (NY): Cold Spring Harbor Laboratory Press; 2009.
Copyright © 2009, The Consortium of Glycobiology Editors, La Jolla, California.

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