FIGURE 6.1. Comparison of amino acid composition of the human, rat and mouse 5-HT2A receptors.

FIGURE 6.1

Comparison of amino acid composition of the human, rat and mouse 5-HT2A receptors. The amino acid sequence of the human 5-HT2A receptor is shown with differences in amino acid residues of the rat and mouse receptors shown above and below the human sequence, respectively. The right panel is a topological depiction of the 5-HT2A receptor. Extracellular and intracellular domains are delineated by the dotted lines depicting the plasma membrane. Amino acid positions where there are differences among various isoforms have been depicted by unfilled circles.

From: Chapter 6, Serotonin 2A (5-HT2A) Receptor Function: Ligand-Dependent Mechanisms and Pathways

Cover of Serotonin Receptors in Neurobiology
Serotonin Receptors in Neurobiology.
Chattopadhyay A, editor.
Boca Raton (FL): CRC Press; 2007.
Copyright © 2007, Taylor & Francis Group, LLC.

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