This figure shows the Summary Receiver Operating Curve (SROC) using bivariate mixed effects model for estimating the area under the curve (AUC) of BNP assay with 95% confidence interval (95% CI) when considering the optimal cut-points of diagnostic studies of heart failure in emergency department settings. Estimated AUC of 31 studies is 0.92 (95% CI: 0.90, 0.94). Each circle denotes one study. The horizontal line represents specificity and vertical line represents sensitivity.

Figure H-12Summary ROC-curve (ED BNP, lowest cut-point), bivariate mixed effect model

From: Appendix H, Key Question 1 Evidence Set

Cover of Use of Natriuretic Peptide Measurement in the Management of Heart Failure
Use of Natriuretic Peptide Measurement in the Management of Heart Failure [Internet].
Comparative Effectiveness Reviews, No. 126.
Balion C, Don-Wauchope A, Hill S, et al.

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