Table 1Trial Selection Criteria for Clinical Evidence

Population Adult and pediatric patients in acute and long-term care facilities, who are infected with or are potential carriers of VRE or ESBL-producing organisms
Intervention
  • Screening (selective or universal) for VRE or ESBL-producing organisms
  • Isolation for VRE or ESBL-producing organisms
  • Decolonization for VRE or ESBL-producing organisms
  • Additional precautions taken in the operating room or post-anesthesia recovery room for patients colonized with VRE or ESBL-producing organisms
Comparator
  • No screening
  • No isolation
  • No decolonization
Outcomes
  • Transmission, infections
  • Intermediate outcomes: VRE or ESBL-producing organism acquisition and infection.
  • Health outcomes: morbidity (including complications of VRE or ESBL-producing organism infection), case-fatality, mortality, quality of care for non-infectious conditions, and medical errors.
  • Adverse events: adverse effects of screening and treatment, including allergic reactions, non-allergic toxicities, and resistance to antimicrobials.
Study design
  • Randomized controlled trials and non-randomized studies

ESBL = extended spectrum beta-lactamase; VRE = vancomycin-resistant enterococci.

From: 4, METHODS

Cover of Screening, Isolation, and Decolonization Strategies for Vancomycin-Resistant Enterococci or Extended Spectrum Beta-Lactamase Producing Organisms: A Systematic Review of the Clinical Evidence and Health Services Impact
Screening, Isolation, and Decolonization Strategies for Vancomycin-Resistant Enterococci or Extended Spectrum Beta-Lactamase Producing Organisms: A Systematic Review of the Clinical Evidence and Health Services Impact [Internet].
Ho C, Lau A, Cimon K, et al.
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