Fig. 1. The structures of the 5′UTR (Rijnbrand and Lemon, 2000) and 3′UTR (Ito and Lai, 1997; Kolykhalov et al.

Fig. 1

The structures of the 5′UTR (Rijnbrand and Lemon, 2000) and 3′UTR (Ito and Lai, 1997; Kolykhalov et al., 1996) of HCV RNA (represented by the HCV-H strain). The structural diagram of the 5′UTR was kindly provided by Drs. René Rijnbrand and Stanley Lemon. psk, pseudoknot. The start codon (nt 342) and stop codon are indicated by boldface characters. The shaded boxes in 5′- and 3′-UTR and are RNA elements putatively involved in RNA replication. The enclosed RNA sequences in 5′-UTR are the reported elements required for efficient IRES-dependent translation.

From: Chapter 2, HCV 5′ and 3′UTR: When Translation Meets Replication

Cover of Hepatitis C Viruses
Hepatitis C Viruses: Genomes and Molecular Biology.
Tan SL, editor.
Norfolk (UK): Horizon Bioscience; 2006.
Copyright © 2006, Horizon Bioscience.

NCBI Bookshelf. A service of the National Library of Medicine, National Institutes of Health.