Table 2-1Blood and Bone Lead Concentrations Corresponding to Adverse Health Effects

AgeEffectBlood leada (µg/dL)Bone leada (µg/g)
ChildrenDepressed ALAD<5ND
ChildrenNeurodevelopmental effects<10ND
ChildrenSexual maturation<10ND
ChildrenDepressed vitamin D>15ND
ChildrenElevated EP>15ND
ChildrenDepressed NCV>30ND
ChildrenDepressed hemoglobin>40ND
ChildrenColic>60ND
Adults (elderly)Neurobehavioral effects>4>30
AdultsDepressed ALAD<5ND
AdultsDepressed GFR<10>10
AdultsElevated blood pressure<10>10
AdultsElevated EP (females)>20ND
AdultsEnzymuria/proteinuria>30ND
AdultsPeripheral neuropathy>40ND
AdultsNeurobehavioral effects>40ND
AdultsAltered thyroid hormone>40ND
AdultsReduced fertility>40ND
AdultsDepressed hemoglobin>50ND
a

Concentration range associated with effect.

ALAD = δ-aminolevulinic acid dehydratase; EP = erythrocyte protoporphyrin; GFR = glomerular filtration rate; NCV = nerve conduction velocity; ND = no data

Concentration range associated with effect.

From: 2, RELEVANCE TO PUBLIC HEALTH

Cover of Toxicological Profile for Lead
Toxicological Profile for Lead.
Abadin H, Ashizawa A, Stevens YW, et al.

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