Figure 6.2. Cause of declining acceleration with age in multistage progression.

Figure 6.2

Cause of declining acceleration with age in multistage progression. The top line shows the six stages that a newborn must pass through in this case. As individuals grow older, many may pass through the early stages. This example shows rapid progression to emphasize the process. Here, most individuals have passed to stage 2 by early life, so the acceleration at this age, the number of steps remaining minus one, is three. By midlife, two steps remain, causing an acceleration of one. By late life, all individuals who have not developed cancer have progressed to the penultimate stage, and so with one stage remaining, they have an acceleration of zero. Redrawn from Frank (2004d).

From: Chapter 6, Theory I

Cover of Dynamics of Cancer
Dynamics of Cancer: Incidence, Inheritance, and Evolution.
Frank SA.
Princeton (NJ): Princeton University Press; 2007.
Copyright © 2007, Steven A Frank.

This book, except where otherwise noted, is licensed under a Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

NCBI Bookshelf. A service of the National Library of Medicine, National Institutes of Health.