Figure 6.3. Distribution of independent lines of progression across various stages, which depends only on n, u, and t.

Figure 6.3

Distribution of independent lines of progression across various stages, which depends only on n, u, and t. Here, n = 10 and t = 80. The stage n = 10 is excluded; that stage causes cancer, and the distributions here show the stages among individuals who have not had cancer. The panels from top to bottom correspond to the parameters for the four curves from top to bottom in Figure 6.1a, plus a fifth value of u = 0.1209, corresponding to m = 0.5 and L = 1, for the distribution in the bottom panel of this figure.

From: Chapter 6, Theory I

Cover of Dynamics of Cancer
Dynamics of Cancer: Incidence, Inheritance, and Evolution.
Frank SA.
Princeton (NJ): Princeton University Press; 2007.
Copyright © 2007, Steven A Frank.

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