Figure 11.9. The relative variance in allele frequencies for rare and common alleles of 74 DNA repair genes.

Figure 11.9

The relative variance in allele frequencies for rare and common alleles of 74 DNA repair genes. The total number of variants in each frequency category is shown above the bars. Each rare variant contributes a small fraction of the total variance, but there are many more rare than common variants. Changes in amino acid sequence define the variants. Data collated by Mohrenweiser et al. (2003).

From: Chapter 11, Inheritance

Cover of Dynamics of Cancer
Dynamics of Cancer: Incidence, Inheritance, and Evolution.
Frank SA.
Princeton (NJ): Princeton University Press; 2007.
Copyright © 2007, Steven A Frank.

This book, except where otherwise noted, is licensed under a Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

NCBI Bookshelf. A service of the National Library of Medicine, National Institutes of Health.