Appendix Table C18Patient characteristics: oral selective antihistamine versus oral decongestant

Author, YearDrug, Dose/DaynMean Age, yearsSex, % femaleRace, %Disease Duration, yearsMean Baseline NSSa
Bronsky., 1995Loratadine 10 mg217Median: 30
Range: 12-60
57.5White: 87.3
Black: 4.2
Other: 8.5
Median: 15
Range: 1-50
Pseudoephedrine 240 mg220Median: 28
Range: 12-60
51.2White: 92.9
Black: 1.9
Other: 5.2
Median: 15
Range: <1-50
Chervinsky, 2005Desloratadine 5 mg2143769Unspecified19C: 2.56
Pseudoephedrine 240 mg2223665Unspecified19C: 2.56
Grosclaude, 1997Cetirizine 10 mg23132
Range: 12-66
52Unspecified8C: 2.28
R: 2.07
S: 2.02
I: 1.76
Pseudoephedrine 240 mg22334
Range: 12-65
51Unspecified8C: 2.24
R: 2.00
S: 1.99
I: 1.79
Grubbe, 2009Desloratadine 5 mg19837
Range: 12-76
65.2White: 77
Black: 13
Hispanic: 7
Asian: 2
Other: 2
17.9
Range: 2-56
C: 2.50
Pseudoephedrine 240 mg20035
Range: 12-68
62.0White: 82
Black: 10
Hispanic: 4
Asian: 3
Other: 2.5
18.0
Range: 2-54
C: 2.46
Pleskow, 2005Desloratadine 5 mg37235
Range: 12-76
65.9White: 80
Black: 12
Hispanic: 7
Asian: <1
Other: 0
18.0
Range: 2-55
Pseudoephedrine 240 mg37736
Range: 12-70
65.5White: 78
Black: 10
Hispanic: 9
Asian: 1
Other: 2
17.9
Range: 2-50
Schenke, 2002Desloratadine 5 mg34034.860Unspecified18.3C: 2.57
Pseudoephedrine 240 mg34234.265Unspecified17.6C: 2.54
Sussman, 1999Fexofenadrine 120 mg21834.9 ( 12.35)
Range: 12-64
56.9White: 85.3
Black: 6.0
Asian: 8.3
Other: 0.5
15.2 (9.79)
Range: 2.0-46.2
C: 2.36 (SE 0.03)*
Pseudoephedrine 240 mg21831.7 (11.12)
Range: 12-66
58.7White: 89.0
Black: 4.1
Asian: 5.5
Other: 1.4
15.9 (10.06)
Range: 1.0-46.0
C: 2.34 (SE 0.03)

C = congestion; I = itching; n = patients randomized to comparator groups of interest; NSS = nasal symptom score; R = rhinorrhea; S = sneezing; SE = standard error; TNSS = total nasal symptom score.

a

Individual symptoms rated on a scale from 0 (no symptoms) to 3 (severe symptoms) in all cases except Sussman 1999, where the maximum was 4.

From: Appendix C, Evidence Tables

Cover of Treatments for Seasonal Allergic Rhinitis
Treatments for Seasonal Allergic Rhinitis [Internet].
Comparative Effectiveness Reviews, No. 120.
Glacy J, Putnam K, Godfrey S, et al.

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