Figure 9. Two representative fields showing profound restoration of lysosomal GAA in patient-derived fibroblasts (blue arrows), upon five day incubation with 20 μM probe compound ML247.

Figure 9Two representative fields showing profound restoration of lysosomal GAA in patient-derived fibroblasts (blue arrows), upon five day incubation with 20 μM probe compound ML247

Coloring scheme is the same as Figure 8.

From: Discovery, SAR, and Biological Evaluation of a Non-Inhibitory Chaperone for Acid Alpha Glucosidase

Cover of Probe Reports from the NIH Molecular Libraries Program
Probe Reports from the NIH Molecular Libraries Program [Internet].

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