Figure 3.. Molecular basis of the neuro-cardiofaciocutaneous syndromes.

Figure 3.

Molecular basis of the neuro-cardiofaciocutaneous syndromes. The Ras/MAPK pathway transmits signals from the cell surface to the nucleus. Mutations in genes encoding different components of this pathway result in different syndromes with overlapping clinical findings.

Adapted from Bentires-Alj et al [2006].

From: Costello Syndrome

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