Table 1Stakeholder prioritization of research gap questions

Question Ranking*Total (Points)PICOTS Element
Methodological Topics Needing Consensus (n=5)
Tier 1: High Priority
Which patient characteristics confound/modify effectiveness of rehabilitation programs?8P
What outcomes of multidisciplinary rehabilitation are most important to:
  • Patients
  • Families
  • Payers
7O
Tier 2: Moderate Priority
How should patient readiness for multidisciplinary rehabilitation programs be measured?5.8P, I
Which injury characteristics confound/modify effectiveness of rehabilitation programs?4.8P
What typology should be used to classify multidisciplinary rehabilitation programs?3I
Tier 2: Low Priority
Which intermediate outcomes adequately predict patient-centered outcomes (surrogate outcomes)?1O
What are the MCIDs for outcomes instruments?
  1. What are the advantages and disadvantages to using MCIDs in research on this topic?
Should they be used to measure program effectiveness?
0.3O
Topical Questions Needing Trials (n=4)
Tier 1: High Priority
Timing: At what stage of recovery do multidisciplinary rehabilitation programs offer the best chance of improvement to patients?7.5T
Which multidisciplinary rehabilitation programs are “promising practices?”
  1. What benefits are experienced by patients participating in various multidisciplinary rehabilitation programs?
  2. What outcomes appear to be most improved by various multidisciplinary rehabilitation programs?
  3. Which patients (subgroups) appear to benefit most by various multidisciplinary rehabilitation programs?
  4. What kinds of harms are experienced by patients participating in various multidisciplinary rehabilitation programs?
5.5I
Sustainability and Followup: Are benefits received from multidisciplinary rehabilitation programs sustained over the long-term?
  • What level and type of followup care allows for maintenance or prevents deterioration of rehabilitation gains at given time periods post rehabilitation?
5O, T
Tier 2: Moderate Priority
Intervention Characteristics: Which intervention characteristics predict response in various forms of multidisciplinary rehabilitation programs?3.3I
Multidisciplinary rehabilitation program versus accessible rehabilitation: What is the comparative effectiveness of various types of multidisciplinary rehabilitation programs vs. rehabilitation typically covered by third party payers?2.3
Tier 3: Low Priority
Subgroups: Does the efficacy of specific multidisciplinary rehabilitation programs vary across patient subgroups?0.3P

Abbreviations: MCIDS = minimum clinically important differences; PICOTS = population, intervention, comparison, outcome, timing, and setting

*

Rankings were weighted to create a total point score by assigning questions ranked #1 by stakeholders with 3 points, questions ranked #2 with 2 points, questions ranked #3 by stakeholders with 1 point. A forced ranking was used with responses that recording duplicate ratings.

Rankings were weighted to create a total point score by assigning questions ranked #1 by stakeholders with 3 points, questions ranked #2 with 2 points, questions ranked #3 by stakeholders with 1 point. A forced ranking was used with responses that recording duplicate ratings.

From: Results

Cover of Multidisciplinary Rehabilitation Programs for Moderate to Severe Traumatic Brain Injury in Adults: Future Research Needs
Multidisciplinary Rehabilitation Programs for Moderate to Severe Traumatic Brain Injury in Adults: Future Research Needs: Identification of Future Research Needs From Comparative Effectiveness Review No. 72 [Internet].
Future Research Needs Papers, No. 36.
Brasure M, Lamberty GJ, Sayer NA, et al.

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