Table F-60Detailed strength of evidence grading table, harms

Intervention, outcomeNumber of Studies; SubjectsRisk of BiasConsistencyDirectnessPrecisionStrength of Evidence Grade
Magnitude of Effect
Topical, serious3, 323MediumConsistentDirectImpreciseInsufficient
No events
Oral, serious5, subjects: NRMediumConsistentDirectImpreciseInsufficient
No events
Topical, mild1, 170MediumUnknown, single studyDirectImpreciseLow, no difference
Oral, mild2, subjects: NRLowConsistentDirectImpreciseInsufficient: no difference

From: Appendix F, Detailed Strength of Evidence Tables

Cover of Otitis Media With Effusion: Comparative Effectiveness of Treatments
Otitis Media With Effusion: Comparative Effectiveness of Treatments [Internet].
Comparative Effectiveness Reviews, No. 101.
Berkman ND, Wallace IF, Steiner MJ, et al.

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