Figure F-83 is titled “PTSD symptom reduction for seeking safety therapy compared with control, by type of comparator.” The figure displays a forest plot reporting the standardized mean difference in PTSD symptom scores stratified by seeking safety therapy versus RPC, seeking safety therapy versus psychoeducation, and seeking safety therapy versus usual care. The plot depicts greater reductions in PTSD symptom scores for patients treated with RPC than seeking safety therapy (2 trials, standardized mean difference 0.02, 95% CI −0.37 to 0.42, I2=18.1%) and patients treated with psychoeducation than seeking safety therapy (1 trial, standardized mean difference 0.07, 95% CI −0.13 to 0.28). On the other hand, the plot also depicts greater reductions in PTSD symptom scores for patients treated with seeking safety therapy than usual care (1 trial, standardized mean difference −0.04, 95% CI −0.40 to 0.33). The overall analysis favored control (standardized mean difference 0.04, 95% CI −0.12 to 0.20, I2=0.0%).

Figure F-83PTSD symptom reduction for seeking safety therapy compared with control, by type of comparator

Timing of outcome assessment: 12 weeks (Hien, 2004), 6 to 8 weeks (Zlotnik, 2009), 6 weeks (Hien, 2009), 12 weeks (Boden, 2012).

From: Appendix F, Meta-Analysis

Cover of Psychological and Pharmacological Treatments for Adults With Posttraumatic Stress Disorder (PTSD)
Psychological and Pharmacological Treatments for Adults With Posttraumatic Stress Disorder (PTSD) [Internet].
Comparative Effectiveness Reviews, No. 92.
Jonas DE, Cusack K, Forneris CA, et al.

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