CID/ML#Target NameEC50 (μM) [SID, AID]Anti-target Name(s)EC50 (μM) [SID, AID]Fold SelectiveSecondary Assay(s) Name: [SID, AID]
CID 56587900/ML292rmGlu4 hmGlu41.20 ± 0.12 (human), 0.33 ± 0.09 (rat)
[SID 134213607,AID 623875, AID 623876]
mGlu1,mGlu2, mGlu3, mGlu5, mGlu6, mGlu7, mGlu8, PanLabs (Ricerca), Millipore>10 μM, [mGlu1–3,7,8; AID 623874, AID 623878, AID 623879, AID 623893, AID 623892], 0.3 FS, mGlu5 (antagonist) [AID 623890], 4.3 FS, mGlu6 (PAM) [AID 623891]>2030.2 ± 2.2 (rat) mGlu4 Fold-Shift [SID 134213607, AID 623889]

From: Discovery of a novel metabotropic glutamate receptor 4 (mGlu4) positive allosteric modulator (PAM) extended probe

Cover of Probe Reports from the NIH Molecular Libraries Program
Probe Reports from the NIH Molecular Libraries Program [Internet].

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