CID/ML#Target NameIC50/EC50 (nM) [SID, AID]Anti-target Name(s)IC50/EC50 (μM) [SID, AID]Fold SelectiveSecondary Assay(s) Name: IC50/EC50 (nM) [SID, AID]
CID 49830258

ML240
p97ATPase110nM [SID 10390416, AID 504650]170 Kinase Panel<50% I at 20 μMN/ACaspase 3/7(SW403): 29-fold at 10,000 nM [SID 103904169, AID 504653]
UbG76V-GFP900nM [SID 10390416, AID 504649]ODD-Luc28,000nM [SID103904169, AID 504654]31-fold
CID 49830260

ML241
p97ATPase110nM [SID 10390418, AID 504650]170 Kinase Panel>50% I at 20 μM (JAK1, PIP5K3, DNAPK)N/ACaspase 3/7(SW403): No Activation up to 20,000 nM [SID 103904185, AID 504653]
UbG76V-GFP3,500nM [SID 10390418, AID 504649]ODD-Luc46,000nM [SID103904185, AID 504654]13-fold

From: Selective, reversible inhibitors of the AAA ATPase p97

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