Table G26Strength of evidence for subgroup effects of severity of exposure to trauma

Outcome: Number of Studies, Number of SubjectsRisk of Bias; Design/QualityConsistencyDirectnessPrecisionMagnitude of Effect: Summary Effect Size (95% CI)Strength of Evidence
Incidence of PTSD: 0; 0NANANANANAInsufficient
PTSD symptom severity: 1; 2,443MediumaUnknownbDirectNot reportedcNot reportedInsufficientd
Depression symptom severity:0; 0NANANANANAInsufficient
Quality of Life: 0; 0NANANANANAInsufficient
Return to work/return to active duty or ability to work: 0; 0NANANANANAInsufficient
Incidence of self-injurious or suicidal thoughts, attempts, or behaviors (including suicide): 0; 0NANANANANAInsufficient
Incidence of aggressive or homicidal thoughts, attempts, or behaviors (including homicide): 0; 0NANANANANAInsufficient
Perceived utility: 0; 0NANANANANAInsufficient
a

Unmasked RCT

b

Downgraded as a single study

c

Downgraded for unclear precision

d

Insufficient SOE because findings reported by only one medium risk of bias trial and magnitude and precision not reported.

Abbreviations: CI = confidence interval; NA = not applicable; PTSD = posttraumatic stress disorder; RCT = randomized controlled trial; SOE = strength of evidence

Unmasked RCT

Downgraded as a single study

Downgraded for unclear precision

Insufficient SOE because findings reported by only one medium risk of bias trial and magnitude and precision not reported.

From: Appendix G, Psychological, Pharmacological, and Emerging Interventions: Strength-of-Evidence Grades

Cover of Interventions for the Prevention of Posttraumatic Stress Disorder (PTSD) in Adults After Exposure to Psychological Trauma
Interventions for the Prevention of Posttraumatic Stress Disorder (PTSD) in Adults After Exposure to Psychological Trauma [Internet].
Comparative Effectiveness Reviews, No. 109.
Gartlehner G, Forneris CA, Brownley KA, et al.

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