Table G21Strength of evidence comparing light versus deep sedation

Outcome: Number of Studies; Number of Subjects; DesignRisk of BiasConsistencyDirectnessPrecisionMagnitude of Effect: Summary Effect Size (95% CI)Strength of Evidence
Incidence of PTSD: 0,0NANANANANAInsufficient
PTSD symptom severity: 1; 135; RCTMediumaNAbDirectNot reportedcSimilar effects (10% vs. 9% with PTSD symptoms)Insufficient
Quality of Life: 0; 0NANANANANAInsufficient
Return to work/return to active duty or ability to work: 0; 0NANANANANAInsufficient
Incidence of self-injurious or suicidal thoughts, attempts, or behaviors (including suicide): 0; 0NANANANANAInsufficient
Incidence of aggressive or homicidal thoughts, attempts, or behaviors (including homicide) 0; 0NANANANANAInsufficient
Perceived utility: 0; 0NANANANANAInsufficient
a

Unmasked RCT

b

Downgraded as a single study

c

Downgraded for unclear precision

Abbreviations: CI = confidence interval; NA = not applicable; PTSD = posttraumatic stress disorder; RCT = randomized controlled trial

From: Appendix G, Psychological, Pharmacological, and Emerging Interventions: Strength-of-Evidence Grades

Cover of Interventions for the Prevention of Posttraumatic Stress Disorder (PTSD) in Adults After Exposure to Psychological Trauma
Interventions for the Prevention of Posttraumatic Stress Disorder (PTSD) in Adults After Exposure to Psychological Trauma [Internet].
Comparative Effectiveness Reviews, No. 109.
Gartlehner G, Forneris CA, Brownley KA, et al.

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