Table 3Results on exemplars applied to six evidence frameworks

OutcomesTang et al.13GRADE14HASTE15Community Preventive Services Task Force16Australian NHMRC17NHS Health Development Agency18
Household Water Chlorination
Water QualityGrade 1 level 1 Strong[plus sign in circle][plus sign in circle][plus sign in circle][plus sign in circle] High quality of evidenceGrade 1- StrongStrong“B” - Good“A”
DiarrheaGrade 2b level 1 possible[plus sign in circle][plus sign in circle][plus sign in circle] Moderate quality of evidenceGrade 2b - PossibleStrong“C” - Satisfactory“B”
Preventing Mother-to-Child Transmission, All Regimens Included
HIV infection in child within year of birthGrade 2b level 1 possible^[plus sign in circle][plus sign in circle][plus sign in circle][plus sign in circle] High quality of evidenceGrade 1- StrongStrong“A” - Excellent“A”
Lay health workers in primary or community health care to reduce mortality and morbidity in children under age 5, compared with usual care
Mortality and MorbidityGrade 2b Level 2 Possible*[plus sign in circle][plus sign in circle] Low quality of evidenceGrade 3 - InsufficientStrong“B” - Good“C”
*

Grade 2c Level 2 if repeatability outside Southeast Asia is not considered acceptable.

^

Tang et al. grade for PMTCT is due to strict rule that only interventions with relative risk (RR)>2 qualify as “strong” evidence. If this rule is flexible we would rate PMTCT as “Grade 1 Level 1 Strong” by Tang et al. categorizations.

Grade 2c Level 2 if repeatability outside Southeast Asia is not considered acceptable.

Tang et al. grade for PMTCT is due to strict rule that only interventions with relative risk (RR)>2 qualify as “strong” evidence. If this rule is flexible we would rate PMTCT as “Grade 1 Level 1 Strong” by Tang et al. categorizations.

From: Results

Cover of Global Health Evidence Evaluation Framework
Global Health Evidence Evaluation Framework [Internet].
Shekelle PG, Maglione MA, Luoto J, et al.

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