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Cherry MG, Greenhalgh J, Osipenko L, et al. The Clinical Effectiveness and Cost-Effectiveness of Primary Stroke Prevention in Children with Sickle Cell Disease: A Systematic Review and Economic Evaluation. Southampton (UK): NIHR Journals Library; 2012 Nov. (Health Technology Assessment, No. 16.43.)

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The Clinical Effectiveness and Cost-Effectiveness of Primary Stroke Prevention in Children with Sickle Cell Disease: A Systematic Review and Economic Evaluation.

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1Assessment aims

The review assessed the clinical effectiveness and cost-effectiveness of primary stroke prevention treatments for children with sickle cell disease (SCD) who were identified by transcranial Doppler (TCD) ultrasonography to be at high risk of stroke. The review examined the existing health economics evidence and identified the key economic issues related to primary stroke prevention treatment in clinical care for this group of patients. A de novo economic model was developed and populated to evaluate the cost-effectiveness of TCD ultrasonography with blood transfusion as a primary stroke prevention treatment within the NHS.

© 2012, Crown Copyright.

Included under terms of UK Non-commercial Government License.

Bookshelf ID: NBK115679
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