Table 24Strength of evidence for MgSO4 versus placebo

ComparisonOutcome (N Studies; N Patients)Strength of Evidence DomainsStrength of Evidence
ROBConsistencyDirectPrecision
MgSO4 vs placeboPain intensity–VAS (3; 238)ModerateConsistentDirectPreciseModerate
MgSO4 vs placeboPain reduction (2; 72)ModerateInconsistentDirectNot pooledInsufficient
MgSO4 vs placeboHeadache recurrence (2; 196)ModerateConsistentDirectImpreciseLow
MgSO4 vs placeboHeadache response at (60 min) (1; 120)ModerateUnknownDirectPreciseInsufficient

MgSO4 = magnesium sulfate; N = number; ROB = risk of bias; VAS = visual analogue scale

From: Results

Cover of Acute Migraine Treatment in Emergency Settings
Acute Migraine Treatment in Emergency Settings [Internet].
Comparative Effectiveness Reviews, No. 84.
Sumamo Schellenberg E, Dryden DM, Pasichnyk D, et al.

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