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Viswanathan M, Golin CE, Jones CD, et al. Closing the Quality Gap: Revisiting the State of the Science (Vol. 4: Medication Adherence Interventions: Comparative Effectiveness). Rockville (MD): Agency for Healthcare Research and Quality (US); 2012 Sep. (Evidence Reports/Technology Assessments, No. 208.4.)

Cover of Closing the Quality Gap: Revisiting the State of the Science (Vol. 4: Medication Adherence Interventions: Comparative Effectiveness)

Closing the Quality Gap: Revisiting the State of the Science (Vol. 4: Medication Adherence Interventions: Comparative Effectiveness).

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Appendix DComprehensive Evidence Tables

Table D1. Description of intervention and comparison groups (MS Word, 176K)

Table D2. Study characteristics, part 1 (MS Word, 164K)

Table D3. Study characteristics, part 2 (MS Word, 155K)

Table D4. Intervention’s disease focus, goal, and theoretical model (MS Word, 158K)

Table D5. Inclusion and exclusion criteria (MS Word, 163K)

Table D6. Key Questions 1–3 (MS Word, 152K)

Table D7. Key Questions 4–5 (MS Word, 151K)

Table D8. Participant baseline characteristics (MS Word, 223K)

Table D9. Medication adherence outcomes 1 (MS Word, 178K)

Table D10. Medication adherence outcomes 2 (MS Word, 142K)

Table D11. Medication adherence outcomes 3 (MS Word, 91K)

Table D12. Medication adherence outcomes 4 (MS Word, 71K)

Table D13. Medication adherence outcomes 5 (MS Word, 65K)

Table D14. Medication adherence outcomes 6 (MS Word, 59K)

Table D15. Medication adherence subgroup outcomes, part 1 (MS Word, 71K)

Table D16. Medication adherence subgroup outcomes, part 2 (MS Word, 66K)

Table D17. Intervention components, part 1 (MS Word, 159K)

Table D18. Intervention components, part 2 (MS Word, 153K)

Table D19. Intervention components, part 3 (MS Word, 153K)

Table D20. Intervention components, part 4 (MS Word, 153K)

Table D21. Mortality data (MS Word, 51K)

Table D22. Morbidity outcomes 1 (MS Word, 93K)

Table D23. Morbidity outcomes 2 (MS Word, 92K)

Table D24. Morbidity outcomes 3 (MS Word, 72K)

Table D25. Morbidity outcomes 4 (MS Word, 59K)

Table D26. Morbidity outcomes 5 (MS Word, 54K)

Table D27. Morbidity outcomes 6 (MS Word, 50K)

Table D28. Morbidity outcome 7 (MS Word, 50K)

Table D29. Patient satisfaction outcomes 1 (MS Word, 74K)

Table D30. Patient satisfaction outcomes 2 (MS Word, 63K)

Table D31. Patient satisfaction outcomes 3 (MS Word, 55K)

Table D32. Patient satisfaction outcomes 4 (MS Word, 50K)

Table D33. Patient satisfaction outcomes 5 (MS Word, 50K)

Table D34. Patient satisfaction outcomes 6 (MS Word, 50K)

Table D35. Quality of life outcomes 1 (MS Word, 56K)

Table D36. Quality of life outcomes 2 (MS Word, 48K)

Table D37. Health utilization outcomes 1 (MS Word, 75K)

Table D38. Health utilization outcomes 2 (MS Word, 69K)

Table D39. Health utilization outcomes 3 (MS Word, 62K)

Table D40. Costs outcomes 1 (MS Word, 55K)

Table D41. Costs outcomes 2 (MS Word, 52K)

Table D42. Adverse event outcomes 1 (MS Word, 56K)

Table D43. Other subgroup outcomes 1 (MS Word, 64K)

Table D44. Other subgroup outcome 2 (MS Word, 63K)

Table D45. Other subgroup outcome 3 (MS Word, 52K)

Table D46. Applicability (MS Word, 156K)

Abbreviations

95% CI

95% confidence interval

AA(s)

African-American(s)

ACE

Angiotensin-converting enzyme

AD

Antidepressant

Adj

Adjusted

ANCOVA

Analysis of covariance

aOR

Adjusted odds ratio

Approx

Approximately

Appt(s)

Appointment(s)

ARB

Angiotensin receptor blockers

Avg

Average

BL

Baseline

BP

Blood pressure

CAD

Coronary artery disease

CBT

Cognitive behavioral therapy

Chi-sq

Chi-square value

CO

Colorado (Table 1B)

Col

Column

Cont’d

Continued

Couns

Counseling

DBP

Diastolic blood pressure

Diff

Difference

Dl

Deciliter(s)

Dx

Diagnosis

Dz(s)

Disease(s)

ED

Emergency Department

Educ

Education/Educational

EP

Endpoint

Gov’t

Government

HbA1C or HA1C

Hemoglobin A1C

HF

Heart failure

Hg

Mercury

HIV

Human immunodeficiency virus

HMO(s)

Health maintenance organization(s)

HR(s)

Hazards ratio(s)

Hr(s)

Hour(s)

HTN

Hypertension

ICS

Inhaled Corticosteroid

Info

Information

LDL

Low-density lipoprotein

LDL-C

Low-density lipoprotein cholesterol

MD(s)

Medical doctor(s)/Physician(s)

MEMS

Micro-Electro-Mechanical Systems

Mg(s)

Milligram(s)

MI

Myocardial infarction

Mm(s)

Millimeter(s)

Mo(s)

Month(s)

NA

Not applicable

NP(s)

Nurse practitioner(s)

NR, N-RNR

Not reported

NS

Not significant or Not specified

OR

Odds ratio

PA(s)

Physician assistant

PCP(s)

Primary care provider(s)

Pharma

Pharmaceutical

PRD

Pharmacy refill data

PRN

When necessary (from P.R.N., Latin for “pro re nata”)

RCT

Randomized controlled trial

RN(s)

Registered nurse(s)

RR

Risk ratio

Rx(s)

Prescription(s)

SBP

Systolic blood pressure

SCL

Symptom Checklist Depression scale

SCr

Serum creatinine

SD

Standard deviation

SE

Standard error

SG1, SG2,…SGN

Subgroup 1, 2,…N

T1, T2,…TN

Time 1, 2,…N

VA

Veterans Administration

Vs.

Versus

Wk(s)

Week(s)

Yr(s)

Year(s)

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