Figure 19.9. Excitatory and inhibitory connections in the cerebellar cortex and deep cerebellar nuclei.

Figure 19.9

Excitatory and inhibitory connections in the cerebellar cortex and deep cerebellar nuclei. The excitatory input from mossy fibers and climbing fibers to Purkinje cells and deep nuclear cells is basically the same. Additional convergent input onto the Purkinje cell from local circuit neurons (basket and stellate cells) and other Purkinje cells establishes a basis for the comparison of ongoing movement and sensory feedback derived from it. The Purkinje cell output to the deep cerebellar nuclear cell thus generates an error correction signal that can modify movements already begun. The climbing fibers modify the efficacy of the parallel fiber-Purkinje cell connection, producing long-term changes in cerebellar output. (After Stein, 1986.)

From: Circuits within the Cerebellum

Cover of Neuroscience
Neuroscience. 2nd edition.
Purves D, Augustine GJ, Fitzpatrick D, et al., editors.
Sunderland (MA): Sinauer Associates; 2001.
Copyright © 2001, Sinauer Associates, Inc.

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