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Figure 7.9. A neurotransmitter can affect the activity of a postsynaptic cell via two different types of receptor proteins: ionitropic or ligand-gated ion channels, and metabotropic receptors.

Figure 7.9

A neurotransmitter can affect the activity of a postsynaptic cell via two different types of receptor proteins: ionitropic or ligand-gated ion channels, and metabotropic receptors. (A) Ligand-gated ion channels combine receptor and channel functions in a single protein complex. (B) Metabotropic receptors usually activate G-proteins, which modulate ion channels directly or indirectly through intracellular effector enzymes and second messengers.

From: Two Families of Postsynaptic Receptors

Cover of Neuroscience
Neuroscience. 2nd edition.
Purves D, Augustine GJ, Fitzpatrick D, et al., editors.
Sunderland (MA): Sinauer Associates; 2001.
Copyright © 2001, Sinauer Associates, Inc.

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