Table 19Risk of bias–perphenazine versus ziprasidone

StudyItemJudgmentDescription
Lieberman et al. 200523Adequate sequence generation?UNCLEARReported as a stratified randomized trial, with no further details regarding sequence generation.
Allocation concealment?UNCLEARNo information reported regarding allocation concealment.
Blinding?YESReported as a DB: patients and assessors blinded.
Incomplete outcome data addressed?YESITT performed on 96% of patients.
Free of selective reporting?YESProtocol was not available, but outcomes in the methods and results are similar.
Free of other bias?UNCLEARBaseline comparability was unclear. Other sources of bias were not detected.

DB = double-blind; ITT = intention-to-treat

From: Appendix E, Risk of Bias Assessment for Randomized Controlled Trials and Nonrandomized Controlled Trials

Cover of First-Generation Versus Second-Generation Antipsychotics in Adults: Comparative Effectiveness
First-Generation Versus Second-Generation Antipsychotics in Adults: Comparative Effectiveness [Internet].
Comparative Effectiveness Reviews, No. 63.
Abou-Setta AM, Mousavi SS, Spooner C, et al.

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