The Drug Effectiveness Review Project (DERP) is a collaboration of public entities, the Center for Evidence-based Policy and the Oregon Evidence-based Practice Center, who have joined together to produce systematic, evidence-based reviews of the comparative effectiveness and safety of drugs in many widely used drug classes, and to apply the findings to inform public policy and related activities in local settings.

The DERP project produces systematic literature reviews of drug classes using only the highest quality evidence. Reviews are public and have the following components:

• Key Questions - to focus the review

• Evidence Tables - detailing what research was used in the review

• Draft Report - draft of review - only posted for public commentary during public comment review period

• Final Report - final version of systematic review that incorporates or considers public commentary